The Shippen Lab, located at Texas A&M University in College Station, TX, is a research facility dedicated to studying telomeres, the nucleoprotein complexes that protect the ends of chromosomes in eukaryotic organisms. Using the genetically tractable plant Arabidopsis thaliana as a model system, the lab employs biochemical, molecular genetic, and cytological approaches to investigate the structure, function, and maintenance of telomeres, with a particular focus on understanding the role of telomere capping proteins and the telomerase ribonucleoprotein complex.
With its sequenced genome, extensive genetic and transgenic tools, and remarkable tolerance to genome instability, Arabidopsis has proven to be an excellent model for unraveling fundamental processes in telomere biology. The Shippen Lab's research aims to contribute to the broader understanding of telomeres, their molecular evolution, and their crucial roles in conferring genome stability and regulating cell proliferation capacity.
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