Stellate DNA LLC, based in Farmington, CT, is a leading provider of innovative gene editing solutions. Their Gatalyst platform offers an integrated suite of technologies for the design and manufacture of single-stranded DNA donors, enabling high-efficiency, low cell toxicity, and large-size knock-ins of payloads using the CRISPR-Cas9 system. With their proprietary DNA donor technology and superior integration efficiency, Stellate DNA is revolutionizing the field of gene editing and cell engineering, with potential applications in diverse areas of the life sciences.
Utilizing clonal synthesis, the Stellate DNA Gatalyst platform ensures customizable gene knock-in payloads at large scale, guaranteeing well-controlled cost, minimal mutation rate, and sequence uniformity. Their circular form of the Gatalyst donor minimizes non-homologous interactions and degradation, resulting in a longer half-life compared to linearized single-strand donors. With a flexible design and the ability to advance the gene editing field into a high-throughput era, Stellate DNA is poised to expedite cell engineering, animal model generation, and therapeutic research.
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