NexoBrid is a bromelain-based enzymatic agent that effectively removes eschar in adults with deep partial thickness and/or full thickness burn wounds, while preserving viable tissue. It is available as a 5g lyophilized powder mixed in a 50g gel vehicle for topical use only, and studies have shown that it dissolves eschar within a 4-hour application period, providing a more precise wound depth determination and earlier medical planning for healing and care.
NexoBrid may offer an alternative option to surgical excision, as it achieved 95% eschar removal in 93% of patients in clinical studies. By selectively removing eschar, NexoBrid allows healthcare professionals to have a clear view of the extent of the original injury, aiding in the treatment process. It is important to note that NexoBrid is contraindicated in patients with known hypersensitivity to bromelain or any other components, and its safety and effectiveness have not been established for certain types of burns or in patients with specific medical conditions.
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