Monon Bioventures LLC, 11227 Knightsbridge Ln, Fishers, IN 46037, US

Hashino Lab, located in Indianapolis, IN, is a research facility dedicated to studying the development and pathology of neurosensory systems, particularly the inner ear, using human pluripotent stem cells in 3D culture. Their expertise in CRISPR Cas9 genome technology allows them to generate inner ear brain organoids with disease-associated mutations and reporter stem cell lines for cell lineage identification. Their ongoing research projects focus on investigating inner ear neurodevelopmental disorders, understanding the genetic and epigenetic mechanisms of inner ear development, and identifying potential chemical compounds for regenerating sensory hair cells in the human inner ear. With a strong emphasis on biomedical research and translational applications, Hashino Lab utilizes organoids, self-organizing structures derived from pluripotent stem cells, to mimic the structural organization and functionality of in vivo organ counterparts. Their cutting-edge work aims to unravel the mysteries of inner ear development and disease, offering insights into genetic mutations that affect inner ear structure and function, and exploring potential strategies for delaying or reversing abnormal development. By combining 3D stem cell biology and advanced modeling techniques, Hashino Lab is at the forefront of research in the field of inner ear development and disease.Generated from the website