The Smith-Magenis Research Foundation (SMSRF) in Miramar, FL is dedicated to supporting research aimed at improving the knowledge and understanding of Smith-Magenis Syndrome (SMS) in order to develop viable therapeutic options and enhance the quality of life for individuals with SMS. They offer an annual grant program to fund innovative research ideas from both new and experienced researchers interested in SMS, with a focus on gaining a deeper understanding of RAI-1 and its role in brain development, exploring gene therapy and small molecule models, investigating the neurobiology of cognitive and maladaptive behavior in SMS, and developing novel therapeutic approaches. The SMSRF provides funding of up to $75,000 in direct costs, with a possibility of extension based on results, and all proposals undergo peer review by the SMSRF Scientific Advisory Panel.
The SMSRF encourages collaboration and intellectual discussion within the SMS research community, aiming to foster advancements in the field towards therapeutic interventions. Researchers interested in applying for grants are required to submit a brief concept paper for initial review, followed by a full proposal if deemed suitable. The concept paper should include a cover letter introducing the investigator(s), the project's goals, and its alignment with the SMSRF's mission. The full proposal should provide a comprehensive overview of the project, including objectives, study design, evaluation measures, expected outcomes, and a timeline. The SMSRF's grant program seeks to support projects that will benefit the SMS scientific community and ultimately translate into clinical therapeutic benefits for individuals with SMS.
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