Though owner and longtime Sierra Madre resident Paul Mansour may be kidding when he says he's been at this location for 100 years, you might not know it when you see that all his customers know his name, and he knows just what they need. He's a PharmD, CCN, and you can find just about any prescription possible. In front of the register you'll find everything from tea tree oil to Emergen-C. Additionally, Best Buy Drugs sells t-shirts, toys, games, greeting cards, and features a copy and fax machine.